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Doxycycline and minocycline (Tetracycline based anti-malarial)
Use of Doxycycline and minocycline: Prevention of Malaria
Brand Names of Doxycycline and Minocycline include, Doxylin, Declomycin,
Doryx, Dynacin, Minocin, Monodox, Terramycin, Vibramycin and Vibra-Tabs
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- not recommended during the last half of pregnancy or while breast feeding.
- not recommended for children under 8 years old
- causes increased sensitivity to sunlight. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking this medicine:
- Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
- Wear protective clothing, including a hat. Also, wear sunglasses.
- Apply a sun block product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your health care professional.
- Apply a sun block lipstick that has an SPF of at least 15 to protect your lips.
- Do not use a sunlamp or tanning bed or booth.
- You may still be more sensitive to sunlight or sunlamps for 2 weeks to several months or more after stopping this medicine. If you have a severe reaction, check with your doctor.
Interaction with other medicines:
- Antacids
- Calcium supplements such as calcium carbonate
- Cholestyramine (e.g., Questran)
- Choline and magnesium salicylates (e.g., Trilisate)
- Colestipol (e.g., Colestid)
- Iron-containing medicine
- Laxatives (magnesium-containing)
- Magnesium salicylate (e.g., Magan)Use of these medicines with tetracyclines may decrease the effect of tetracyclines
- Oral contraceptives (birth control pills) containing estrogenUse of birth control pills with tetracyclines may decrease the effect of the birth control pills and increase the chance of unwanted pregnancy
- PenicillinsUse of tetracyclines with penicillins may decrease the effect of penicillins
Interaction with other medical problems
- Diabetes insipidus (water diabetes)Demeclocycline may make the condition worse
- Kidney disease (does not apply to doxycycline or minocycline)Patients with kidney disease may have an increased chance of side effects
- Liver diseasePatients with liver disease may have an increased chance of side effects if they use doxycycline or minocycline
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